Motif ID: FOX{C1,C2}.p2

Z-value: 1.246


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXC1chr6_+_1556543-0.381.6e-01Click!
FOXC2chr16_+_851583570.361.9e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_169392771 2.774


chr17_-_78391178 2.481 NM_024702
 ZNF750
zinc finger protein 750
chr22_+_19239221 2.052 MED15
mediator complex subunit 15
chr20_-_60435983 1.804 NM_080833
 C20orf151
chromosome 20 open reading frame 151
chr18_+_41558141 1.637 SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr8_+_55691179 1.547 NM_006269
 RP1
retinitis pigmentosa 1 (autosomal dominant)
chr2_+_73973600 1.491 NM_001615
 ACTG2
actin, gamma 2, smooth muscle, enteric
chr6_+_47732181 1.454 NM_153839
 GPR111
G protein-coupled receptor 111
chr7_-_98643024 1.439 NM_001145715
 KPNA7
karyopherin alpha 7 (importin alpha 8)
chr7_-_99115454 1.433 NM_000777
NM_001190484
 CYP3A5

cytochrome P450, family 3, subfamily A, polypeptide 5

chr2_+_73973640 1.419 ACTG2
actin, gamma 2, smooth muscle, enteric
chr11_+_111288686 1.231 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr3_+_137224266 1.226 NM_181897
 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr15_-_56093477 1.150 NM_170697
 ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr1_-_26553168 1.110 NM_001039775
 AIM1L
absent in melanoma 1-like
chr2_-_233349469 1.104 NM_001172416
NM_001172417
NM_002242
 KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr1_+_150958621 1.101 NM_001024679
 C1orf68
chromosome 1 open reading frame 68
chr11_+_111288669 1.058 NM_001541
 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr17_-_39191658 1.040 NM_025237
 SOST
sclerostin
chr1_-_110735158 1.022 NM_004696
 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.87 3.00e-10 GO:0007608 sensory perception of smell
3.47 1.05e-08 GO:0007606 sensory perception of chemical stimulus
2.39 2.65e-05 GO:0007600 sensory perception
1.80 1.01e-02 GO:0050877 neurological system process
1.76 1.97e-03 GO:0003008 system process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.73 5.16e-03 GO:0005578 proteinaceous extracellular matrix
2.62 2.89e-03 GO:0031012 extracellular matrix
1.47 2.47e-05 GO:0005886 plasma membrane
1.46 3.62e-05 GO:0071944 cell periphery
1.31 4.19e-04 GO:0044425 membrane part
1.27 2.93e-02 GO:0031224 intrinsic to membrane
1.27 3.21e-02 GO:0016021 integral to membrane
1.20 4.08e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.06 1.45e-11 GO:0004984 olfactory receptor activity
2.55 1.13e-07 GO:0004930 G-protein coupled receptor activity
2.17 3.49e-03 GO:0005509 calcium ion binding
1.94 1.47e-04 GO:0004888 transmembrane receptor activity
1.74 5.52e-04 GO:0004872 receptor activity
1.66 4.96e-04 GO:0004871 signal transducer activity
1.66 4.96e-04 GO:0060089 molecular transducer activity